Jinan Jiage Biological Technology Co, Ltd

Jinan Jiage Biological Technology Co, Ltd

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  • Company Name: Jinan Jiage Biological Technology Co, Ltd
  • Street: No 28, Sankongqiao Road, Tianqiao District, Jinan
  • City: Jinan
  • Province/state: Shandong
  • Country/region: China
  • Contact Person: Ms.Lillian Cao
  • Department: Sales
  • Tel: 86-0531-15564141272
  • Fax: 86-0531-85826061
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Tamoxifen

  • CAS No:54965-24-1 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,<br />N-dimethylethanamine
    Molecular Structure

    Detailed Description

    Tamoxifen
    Chemical name:(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxyl]-N,N-dimethyl-ethanamine-citrate;
    1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate
    Synonyms:Nolvadex
    CAS NO: 54965-24-1
    Molecular formula:C26H29NO.C6H8O7
    Molecular weight: 563.64
    Purity:99%
    State:solid
    Suitable for:Elderly, Children, Adult
    Apperance:White Crystalline Powder
    Certification:SGS
    Usage:Hormones and Regulation of Endocrine Function of Drug, Cardiovascular Agents, Respiratory System Agents
    Description:
    Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a selective estrogen-receptor modulator. Tamoxifen is the usual endocrine (anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.
    Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor, blocking cancer cell growth.
    Tamoxifen was discovered by pharmaceutical company Imperial Chemical Industries(now AstraZeneca) and is sold under the trade names Nolvadex, Istubal, Valodex, and Genox. However, the drug has been widely referred to by its generic name "tamoxifen", even before its patent expiration.
    It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
    Application:
    Nolvadex is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not our strongest available remedy.
    Nolvadex is an estrogen agonist in the liver, capable of activating the estrogen receptor and mimicking the actions of this sex hormone in this region of the body. As such it can have a markedly positive impact on HDL (good) cholesterol values, as does estrogen.
    Packing:
    Discreet packing ways as your requirement, 100% go through.
    Storage:
    Store in cool and dry area and keep away from direct sunlight.
    Advantage:
    1. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years.

    2. Discreet package :The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also taken into consideration .

    3. Top quality :High quality guaranteed, once any problem is found, the package would be reshipped for you .

    4. Security Shipping:Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you.

    5. Fast delivery :we have stock, so we can delivery quickly once payment is received.

    6. Quality service:we will give you warm after-sale service,if any question we will reply you within 24 hours.

    7. Competitive price:A discount would be given when you make a large order.